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Obesity affects cancer risk in several biological ways, says Dawn L Hershman, MD, MS, FASCO, Witten Family Professor of Medicine and deputy director of the Herbert Irving Comprehensive Cancer Center at Columbia University

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Other warnings involve severe gastrointestinal adverse reactions, delayed gastric emptying, pancreatitis, gallbladder problems, acute kidney injury related to dehydration, increased heart rate, hypoglycemia when used with certain diabetes medications, and suicidal behavior or thinking