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J Am Coll Cardiol (2006) 47(8 Suppl):C712

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Primarily, there is a significant deficit of human studies evaluating functional aging outcomes rather than just common metabolic indicators, which should include assessments of cognitive ability, physical performance, and physiological resilience

The authors concluded: The use of GLP-1 agonists should be considered in T1DM patients who are overweight or obese and not at glycemic goals despite aggressive insulin therapy. After conducting clinical trials with a GLP-1 agonist, Novo Nordisk decided not to pursue FDA approval for treating type 1 diabetes

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