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However, this study did not measure the confounding factors, and the rate of withdrawal due to adverse drug reactions was not evaluated that limit the studys clinical efficacy

Most clinical trial participants started at 2mg per week as the initial dose, with planned escalation over the following months

These findings are important because they demonstrate that androgen excess begins early in life in the context of obesity, establishing a potential mechanistic link to later reproductive and metabolic disorders such as polycystic ovary syndrome

The most common side effects include: Nausea Vomiting Constipation Diarrhea Acid reflux Abdominal pain Burping or "sulfur burps" Fatigue Some people also notice side effects when increasing their dose a process known as titration but Dr

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Recent reports indicate Novo Nordisk offers Wegovy for around $499 per month via its NovoCare Pharmacy program, and Eli Lilly offers Zepbound for around $349 per month for the starter dose and $499 for higher doses through its self-pay program