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This is not a replacement for any topical or in-office treatment discussed above, but I think it deserves to be part of the same conversation, since it addresses a contributing factor at its source rather than only managing the visible result after the fact

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In addition, the NTS houses numerous neuropeptides that are capable of modulating HPA axis stress responses, including glucagon-like peptide-1 (GLP-1), somatostatin, substance P, neuropeptide Y and enkephalin [15, 18, 35]