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SGLT2i have consistently demonstrated cardiovascular benefits in meta-analyses and recent studies, confirming their robust efficacy regardless of ejection fraction or the presence of diabetes

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The hormonal changes observed in our analysis further contribute to the therapeutic potential of GLP-1RAs, though the impact was less consistent compared to their effects on anthropometric measurements and glucose regulation

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Compounded semaglutide is created by licensed pharmacies using the same active ingredient (semaglutide), but its not FDA-approved

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