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Retatrutide: Phase II data showed up to 24.2% body weight reduction in only 48 weeks

This is generally fine because it still falls within the weekly dosing window and maintains at least 7 days from your previous dose

doi:10.1016/J.JACC.2017.02.046 Honarbakhsh S, Providencia R, Garcia-Hernandez J, et al

Weight loss requires a calorie intake lower than what you typically consume

Similarly, the Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN) studies was a series of 7 RCT that investigated the efficacy and safety of subcutaneous semaglutide in over 8000 patients with type 2 diabetes [12]

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