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transdermal systems may additionally cause local skin reactions

If vial-and-syringe technique feels overwhelming at the start, beginning with a pen and transitioning to vials later is a completely valid approach

doi: 10.2337/dc12-2006 [DOI] [PMC free article] [PubMed] [Google Scholar] 77

instead, their focus is on delivering high protein, fiber, and essential vitamins to help those on GLP-1 therapy maintain adequate nutrition within reduced portion sizes

The SURMOUNT-1 trial demonstrated a 15 mg dosage of tirzepatide in non-diabetic obese subjects leads to 20.9% weight loss at week 72 with sustained weight loss during a 3-year extension period [134,137]

Semaglutide (Ozempic) is an analogue of human GLP1 RA and is linked via a hydrophilic spacer and a fatty acid side chain to albumin (282)