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Mechanism of Action Trulicity (Dulaglutide): Trulicity is a once-weekly GLP-1 RA

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Annu Navani, MD, longevity and biohacking expert and chief medical officer at Boomerang Healthcare

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Its simultaneous activation of three receptor pathways GLP-1R for appetite suppression and insulin secretion, GIPR for augmented insulin response and central appetite modulation, and GCGR for energy expenditure and hepatic fat mobilisation produces metabolic effects that exceed what single or dual agonism can achieve [4][8][9]

When Tirzepatide Is the Right Next Step After Semaglutide If youve experienced a plateau on Semaglutide, Tirzepatide can be a highly effective next step