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Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): A 56-week, double-blind, phase 3a, randomised trial

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The data in Figure 13 summarizes the energetic contributions of GLP-1R residues, along with critical, or more precisely, the hotspot amino acids that contribute to GLP-1R activation and insulin exocytosis
J., Dehlendorff, C., & Mrch, L
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While compounded medications can be safe and effective when obtained through legitimate channels, they do not undergo the same FDA review process as brand-name products
