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For example, sitagliptin is primarily eliminated unchanged through the urinary system, while Vildagliptin is metabolized in the kidneys in an inactive metabolites, with about a quarter of it being excreted unchanged in the urine

doi: 10.1007/BF02064202

Food and Drug Administration approved its oral glucagonlike peptide 1 (GLP-1) medication for weight loss and obesity in adults

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Source: Bartelt, et al Epic Research Network October 10, 2023 LIN K Implications for employers: An FDA black box warning says that those with a family or personal history of medullary thyroid cancer should not be prescribed GLP-1 drugs

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