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20 Broughton, D.E
GLP-1 agonists are not appropriate for everyone who wants to lose weight

But for reproductive-age men who may want children, the standard first-line prescription of TRT deserves reconsideration in light of both the fertility risk it carries and the growing evidence that addressing the metabolic cause may be both safer and more effective

The recording chamber, with a volume of 500 L, was continuously superfused at a rate of 12 mL/min

Participants who had been on the medication for 36 weeks (average weight loss of 20.9%) were then randomized to continue or switch to placebo

It is key in controlling processes like mitochondrial biogenesis, fatty acid synthesis, and glucose uptake [66], [67]
