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The OASIS 4 trial evaluated the safety and effectiveness of once-daily semaglutide25 mgin obese and overweight patients without T2DM

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A study found that stopping and restarting GLP-1s could make the drug less effective in weight loss.

As GH levels naturally decline with age, exploring different options for patient care may help personalize treatment strategies

Given these considerations, the therapeutic approach in older patients with T2D is complex, particularly in those who have functional dependence, frailty, dementia, or who are at end-of-life