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They can help regulate appetite, digestion, and blood sugar by communicating a signal of fullness to the brain, which may reduce hunger and lead to weight loss

Although no current evidence suggests that GLP-1RAs induce -catenin mutations or APC deficiencies, it is hypothesized that prolonged use of GLP-1RAs may foster the proliferative progression of colorectal cancer cells and pancreatic -cells, based on their mechanisms of action [99]

However, your bariatric surgeon may suggest taking them to lower your surgical risk and get started on the weight loss path

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doi: 10.1016/j.cell.2025.05.043, 161 ZhangQ.DelessaC

Additionally, talk to a professional about targeted supplementation, which may help you optimize your nutrient levels