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Description

The question has gained visibility due to anecdotal accounts of so-called Ozempic babies. This paper aims to delineate mechanisms linking GLP-1 receptor activation with reproductive outcomes, review clinical data on fertility, and outline implications for practice

Y.LicznerskiP.LeeB.et al

Your body is encountering a new compound with a new receptor profile, and even though two of the three pathways are familiar, the experience is different

Accessed 28 Feb 2020

13 Given these multiple actions, in pediatric models, GLP-1R activation may directly interfere with metabolic plasticity, cellular differentiation, and tissue remodeling, requiring caution regarding potential off-target effects during growth and development