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The approval is based on the Phase III NAPOLI 3 trial, where the Nalirifox regimenwhich combines Onivyde with fluorouracil, oxaliplatin and leucovorinboosted overall survival (OS) by a statistically significant 17% compared to standard of care

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Hybrids 5 and 9 showed efficacy but no improvement, indicated by a similar blood glucose curve to peptide 1 (Fig

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