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Remarkably, microglia have a typical neurodegenerative signature for conditions such as Alzheimer's disease (AD), multiple sclerosis (MS), or Parkinson's disease (PD) (Butovsky and Weiner, 2018), reacting to injury through morphological changes by increasing microglial proliferation, migration to the target, phagocytosis, activating the inflammasome, and releasing proinflammatory molecules (Diz-Chaves et al., 2022b)

Why is Ozempic so hard to get through Medicaid for weight loss?#why-is-ozempic-so-hard-to-get-through-medicaid-for-weight-loss Ozempic has FDA approval for treating Type 2 diabetes, meaning the federal Food and Drug Administration has reviewed the drugs safety and effectiveness

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In a phase 2 clinical trial for obesity, 26 weeks of efinopegdutide (doses 5 to 10mg) resulted in up to 11.8% WL in people with obesity (without diabetes) compared to 7.5% WL with liraglutide 3 mg and 1.8% WL with placebo [77, 78]

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