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Description
The episode underscored a challenge that would become a recurring issue for GLP-1 developers: mechanisms with powerful metabolic effects often carry tolerability trade-offs that cannot be engineered away easily
they are generally less commonly prescribed now due to newer, more convenient options
Recent advancements in healthcare have witnessed an improvement in the prognosis of T2DM patients due to earlier detection and improvements in diabetes care [4]
The GRADE trial provides some insights, reporting a cardiovascular benefit with liraglutide
2022;45:S144S174
Like other biological medications (such as insulin), its structure is delicate and susceptible to degradation from heat, light, and agitation
