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Common early side effects include nausea, constipation, and mild fatigue, which typically decrease within 24 weeks as your body adjusts

You might want to limit particularly sugary drinks such as ciders or alcopops as they can be surprisingly high in calories

However, it will take longer than that before you notice changes in your body or appetite

Promoting lifestyle changes, education and counseling, in addition to traditional medicine, the program focuses on diabetes and pre-diabetes but also addresses related illnesses such as obesity, chronic kidney disease, sleep apnea and liver disease

TGR5 and FXR are expressed in enteroendocrine L-cells in the intestine
