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Methods This retrospective cohort study utilized the TriNetX electronic health record database, a multinational and multi-institutional database

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Nearly 70% of adults in the United States struggle with obesity or being overweight, casting a shadow over their self-confidence and limiting their ability to fully embrace the precious gift of life

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In patients with obesity (mean age 51.3 years, 65.6% women), semaglutide compared with non-GLP-1RA anti-obesity medications was associated with lower risk for incident CUD in patients with no prior history CUD (HR: 0.56, 95% CI: 0.420.75), and recurrent CUD diagnosis in patients with a prior history CUD (HR: 0.62, 95% CI: 0.460.84)

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GLP-1 medications like semaglutide work best when doses increase gradually over weeks and months

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