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Program Structure TRIUMPH consists of four Phase 3, multicenter, randomized, double-blind studies in over 5,800 participants (this strategy is also known as a basket trial): - TRIUMPH-1: Weight management basket trial with nested OSA and OA protocols

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Viral vectors have been used to deliver gene therapy in the clinic and in clinical trials, like in Ultragenyxs gene therapy clinical trial for Sanfilippo type Aa gene therapy carried by the harmless AAV9 virus, which can cross the BBB after intravenous injection via a vein in the arm