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Dominguez says

Additionally, the study did not include the combination of lifestyle interventions with either semaglutide or metformin

Food and Drug Administration (FDA) make it clear that Novo Nordisk knew or should have known about these potential risks, yet failed to conduct thorough research on the semaglutide drugs side effects, placing its desire for profits before consumer safety

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( Epub 2019/04/21 )

The SURPASS program, a series of phase III clinical trials, was conducted to assess the therapeutic efficacy (glycemic control and body weight reduction), safety, and tolerability of tirzepatide in people with T2D
