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A shortage of Adderall, which is used to treat attention deficit hyperactivity disorder, shows little sign of easing as manufacturers struggle to get enough active ingredient to make the drug and demand climbs

For GLP-1 agonist therapy, start with the lowest dose and gradually titrate up to minimize gastrointestinal side effects, following specific dose escalation ...

It is not exactly clear what withdrawing its PMDD indication means

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Pfizers dose-optimization studies of once-daily formulations of danuglipron ( NCT06567327 and NCT06568731 ) met key pharmacokinetic objectives and confirmed a formulation and dose with the potential to deliver a competitive efficacy and tolerability profile in Phase 3 testing, based on earlier studies of twice-daily danuglipron