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On the other hand, vildagliptin and saxagliptin act through a biphasic inhibition process, beginning with the formation of a reversible covalent enzymeinhibitor complex, followed by slow dissociation

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[DOI] [PubMed] [Google Scholar] 22.Fiorentino M, Bolignano D, Tesar V, Pisano A, Biesen WV, Tripepi G, et al

demonstrated that GLP-1RAs are associated with significantly lower risks of pneumonia and severe sepsis in patients with type 2 diabetes compared to dipeptidyl peptidase-4 inhibitors (DPP-4is)