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Glucagon-like peptide 1 and its effects GLP-1 is an stimulating insulin release inhibiting glucagon release slowing gastric emptying reducing appetite by increasing satiety These GLP-1 effects may be impaired or absent in people with type 2 diabetes

doi:10.1002/jcph.443

This study aimed to evaluate the effectiveness and safety of adding tirzepatide to insulin glargine in patients with type 2 diabetes who had inadequate control of blood sugar levels

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Thats not a reason to panic, but it is a reason for appropriate humility about what we can confidently claim