mounjaro tirzepatide pregnancy guidance And Pregnancy: What You Should Know These highlights do not include

Tirzepatide is a dual GIP and GLP-1 agonist

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Tirzepatide is a dual-agonist , meaning it works by targeting two hormones: GLP-1: helps regulate appetite, blood sugar, and digestion GIP: supports insulin response and reduces nausea Retatrutide is a triple-agonist , meaning it targets three hormones: GLP-1: helps regulate appetite, blood sugar, and digestion GIP: supports insulin response and reduces nausea Glucagon: affects energy use and fat metabolism Early studies show that retatrutide may be more successful than tirzepatide at managing diabetic kidney disease, as well as for weight control, while tirzepatide may be better at managing blood glucose

Some peptides help regulate hunger hormones, while others support fat metabolism or hormone signaling related to body composition

Obesity Canada is committed to the implementation of Canadian obesity guidelines,7 , 13 in addition to updating and expanding its knowledge mobilization activities for focused updates

For context, side effects caused about 5% of people to stop semaglutide and about 7% to stop tirzepatide in similar weight-loss trials