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Research shows that very-low-carbohydrate diets may amplify certain side effects of GLP-1 agonists, particularly nausea and constipation, while potentially enhancing weight loss in some individuals

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Andrews and colleagues (2009) demonstrated that MPTP-induced dopaminergic dysfunction is amplified in GHSR KO animals, and selective re-expression of GHSR1a in catecholaminergic neurons of GHSR KO animals reduced this degeneration
