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Indeed, while confusing these two lesion types may have been justified back in 2002, when a letter to the editor published in Diabetes Care proposed a three-stage classification for insulin-related LD despite little being admittedly known about the nature and causes of described phenomena [3, 7, 23]

Control vs Risk Trade-Off 13

[DOI] [PMC free article] [PubMed] [Google Scholar] 1314.Galindo RJ, Pasquel FJ, Fayfman M, et al

When metformin must be discontinued, consultation with endocrinology or nephrology can help optimize the medication regimen, often combining SGLT2 inhibitors and GLP-1 agonists for maximal kidney and cardiovascular protection
