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Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus

How does that work

The higher mortality in T2DM occurs mostly owing to cardiovascular diseases

Soleiman applies decades of clinical decision-making to laboratory interpretation, side-effect management, and riskbenefit counseling for GLP1based therapies

Higher -hydroxybutyrate levels can deactivate the nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome pathway in neutrophils and monocytes/macrophages

Detailed discussions encompass their impact on inflammatory responses, cytokine production, and attenuation of oxidative stress