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Retatrutide may have an edge for visceral fat reduction given the glucagon component effects on liver fat metabolism

Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function
Storgaard, H., Cold, F., Gluud, L
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Results showed that although tirzepatide reduced the risk for DPN by 0.6%, 1.1%, and 1.8% at 1 month, 1 year, and 2 years, respectively, insulin actually increased the risk at each time point (+ 0.2%, + 1.4%, + 1.4%)

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