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The good news: This waiver has been extended multiple times and currently runs through December 31, 2025 (and will likely be extended again)

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The GLP-1 revolution, which started with relatively modest single-agonist drugs, has progressed to dual-agonists, then triple-agonists, and the pipeline continues to expand

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The most common are nausea, vomiting, diarrhea, and constipation, affecting between 20 and 40 percent of patients in the STEP and SURMOUNT trials

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Scientists are still studying exactly how GLP-1 interacts with these areas, but the current understanding is that any effect on reproductive hormones is minimal

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This article summarizes each with attribution and methodology context

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