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There are many obesity-related complications, including type 2 diabetes, heart disease, obstructive sleep apnea, chronic kidney disease, non-alcoholic fatty liver disease, and cancer
Regardless of the specific molecule chosen, medical supervision is a must

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Compared to GLP-1 RAs, no significant difference was observed with SGLT2is (WMD: 160

Healthcare providers should assess for conditions that increase appetite, including uncontrolled diabetes (check HbA1c), thyroid disorders (TSH, free T4), and psychiatric conditions
