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Over the past decade, GLP-1 has emerged not only as an essential component of the system that regulates blood glucose levels but also as a viable therapeutic target for the treatment of type 2 diabetes mellitus

Ben: Yeah, it's interesting that this ended up being more of a manufacturing and scale advantage than an efficacy advantage

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Emerging evidence links variants in GLP1R, GIPR, and FTO genes to metabolic efficiency during caloric restriction

Rather, he thinks their ability to reduce appetite occurs by stimulation of parts of the brain that sit outside the bloodbrain barrier the selective semi-permeable membrane that keeps most large molecules out

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