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In in vitro studies GLP-1 receptor agonism is associated with regulation of several inflammatory pathways, including cytokine production, lypotoxicity and macrophages differentiation

Its the way we treat heart failure, HIV, tuberculosis, blood pressure, and many other diseases in medicine

Glucagonlike peptide 1 (GLP1): an intestinal hormone, Signalling nutritional abundance, with an unusual therapeutic potential

These drugs mimic the action of naturally occurring GLP-1, a hormone produced in the intestines in response to food intake

This makes it an appealing option for individuals struggling with obesity or those requiring weight reduction for health reasons

Additionally, some novel GLP-1s hold promise for improved tolerability, as evidenced by Structure Therapeutics phase 2 data for GSBR-1290, which demonstrated encouraging results in terms of AEs and discontinuation rates