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doi: 10.4158/CS-2019-0472 [DOI] [PubMed] [Google Scholar] 81.Baggio LL, Drucker DJ

Some people experience no gastrointestinal issues with tirzepatide but cannot tolerate semaglutide, or vice versa
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(Biopharma PEG, a leading worldwide PEG derivatives supplier, provides PEG derivatives for PEGylated peptide and protein drugs and a variety of supporting technical services
Camacho-Pereira J, Tarrago MG, Chini CCS, Nin V, Escande C, Warner GM, et al
In the STEP trials, semaglutide 2.4mg weekly resulted in mean weight reductions of 1517% over 68 weeks, whilst tirzepatide in the SURPASS trials showed reductions of 1520% (Kushner et al

Liraglutide treatment is associated with a low frequency and magnitude of antibody formation with no apparent impact on glycemic response or increased frequency of adverse events: results from the Liraglutide Effect and Action in Diabetes (LEAD) trials
