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In patients with diabetes mellitus not achieving targets on lifestyle measures, pharmacologic therapy should be considered

95% CI 0.89, 0.96) and all-cause mortality rate (HR 0.70

While the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron is in-line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury which resolved after discontinuation of danuglipron

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