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DPP-4 inhibitors were introduced for the treatment of type 2 diabetes in 2006

Data on bone health in the context of calorie restriction and bariatric surgery were also summarized

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We also describe the development of incretin-based pharmacotherapy, starting with exendin- 4 and ending with the identification of multi-incretin hormone receptor agonists, which appear to be the next major step in the fight against T2DM and obesity

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