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This initial dose is important for treatment initiation and is typically not intended for glycemic control

"Tirzepatide Once Weekly for the Treatment of Obesity." New England Journal of Medicine, 2022, 387(3), 205-216

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As a result, large numbers of hairs switch prematurely from the active growth phase (anagen) into the resting phase (telogen)

Tirzepatide had finished its last Phase 3 clinical trial SURPASS-5 in February 2022,50 and it favors activating GIPR (for GIPR, native GIP EC 50 : 0.0334nM, tirzepatide EC 50 : 0.0224nM

Month 3+: Continued weight loss, improved metabolic markers, and growing confidence in the medication