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Description
Studies have shown that activation of the TGF-/Smad3 signaling pathway promotes collagen deposition, increases myocardial stiffness, and drives fibrotic remodeling [48]
What is a letter of medical necessity
It is important to know that this is only for the starter doses
For this reason, women using oral hormone therapy should work closely with their healthcare provider to monitor symptoms, consider transdermal routes of application, and use hormone testing to monitor levels
PMCID: PMC5496233
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