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Real-world use and effectiveness of tirzepatide among individuals without type 2 diabetes

The episodes were transient, which suggests they may occur primarily in the beginning of treatment, although studies are needed to determine whether this is the case

48 In vivo models have also shown that GLP-1 RAs positively modulate cardiac remodelling with less cardiac hypertrophy and fibrosis

The clinical consequence shows up in weight-loss outcomes

Additionally, inflammation or muscle strain might be involved, but these links are not well understood yet
