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When semaglutide or similar compounds occupy these receptors, they may modulate dopamine and serotonin signaling, neurotransmitter systems central to mood regulation

Across various non-clinical models, adverse effects have been limited and not widely reported, with most subjects tolerating the compound well

Moreover, insurance coverage varies

doi: 10.1016/J.BCP.2020.114187

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Gatchalian, program manager, Addiction Recovery Research Center, Fralin Biomedical Research Institute at VTC Amber Kelly, graduate student, Translational Biology, Medicine, and Health Graduate Program Alexandra DiFeliceantonio, assistant professor, Fralin Biomedical Research Institute at VTC, associate director, Center for Health Behaviors Research