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Although our focus here is on pancreatic GLP-1, GLP-1 in the circulation, presumably due to intestinally secreted GLP-1, also increases with inflammation and the mechanism by which this occurs has been linked to one particular cytokine, interleukin 6 (IL-6)

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This suggests that GLP1-RAs may be particularly useful in obesity-related mood disorders

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An anal fissure is a small tear in the lining of the anal canal kind of like a paper cut in a very inconvenient place

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Common Side Effects Nausea Vomiting Diarrhea Stomach pain Decreased appetite Serious Side Effects Pancreatitis (severe stomach pain, nausea) Gallbladder issues (gallstones, pain in the upper abdomen) Thyroid tumors (seen in animal studies) Some patients also report feeling still hungry on semaglutide, which may be related to how their body responds to the medicationor differences in dosage or absorption

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Throughout your treatment, youll return for regular follow-up visits so we can monitor your progress, adjust your dosage, and provide ongoing support

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Eli Lilly followed with Zepbound in November 2023

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