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Description
For the vast majority of people with straightforward hypothyroidism (an underactive thyroid gland, most commonly caused by autoimmune thyroiditis or Hashimoto's disease), Wegovy does not directly interfere with thyroid hormone replacement therapy

120 showed that treatment with GLP-1RAs resulted in reduced testosterone levels, which improves hyperandrogenic symptoms and enhances menstrual regularity

GLP-1 receptor agonists and heart failure Heart failure (HF) is a complex and debilitating condition with a substantial global health burden (61)

While murine models suggest atrial GLP-1R expression, the precise cardiac cell types expressing GLP-1R, especially in humans, are yet to be conclusively identified [33]
PubMed Central PMCID: PMC3375920

Bioorg Med Chem (2013) 21(22):706473