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doi: 10.1039/c2np20070h

B.AhmedA.MansonJ

In a meta-analysis, the I-squared statistic does not tell us how much the effect size varies

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In STEP 1-3 clinical trials, a weekly dose of 2.4 mg semaglutide resulted in a 49% reduction in C-reactive protein (CRP) levels, while a 1 mg weekly dose led to a 42% decrease, compared to placebo after 68 weeks

cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina) occurred in 109 participants
