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So, what exactly is microdosing GLP-1s, how does it work, and is it right for you

Other important safety considerations include risk of hypoglycaemia when combined with insulin or sulfonylureas, potential gallbladder disease, and the need for monitoring in patients with pre-existing diabetic retinopathy

The risk of generalised skin reactions, such as widespread rash or urticaria, appears to be low based on current evidence, though trial populations may not fully reflect the diversity of patients who would use the medication in routine clinical practice

To reduce side effects Nausea, vomiting, constipation and fatigue are among the most common side effects of GLP-1 drugs, and how hard they hit can depend, at least in part, on the dose

You start at a low dose and escalate gradually to minimize side effects, and you stay at your peak dose until you reach your target weight or plateau

2023;58 doi: 10.1016/j.eclinm.2023.101882