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Weight loss was significant in both groups (from an average of 112 kg to an average of 91.8 kg in the KD group and from an average of 106.5 kg to an average of 84.1 kg in the LCD group, without a statistically significant difference between the groups)

The author concludes that prophylactic use of PPIs must be carefully considered and may not be worth the risk

Any retatrutide currently in circulation outside of formal clinical trials is typically supplied as a research-grade lyophilised (freeze-dried) powder, intended strictly for laboratory or research purposes

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Detailed baseline characteristics are listed in Table 1 and Additional file 2