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Look into patient assistance programs offered by Novo Nordisk, which makes Ozempic and Wegovy

Mice given 0.4 mg/Kg GLP-1 showed better colon protection effect (increased colon length and decreased inflammatory cytokine secretion) than mice given 0.1 and 0.2 mg/Kg GLP-1 at low and medium doses, but no difference in weight loss

Researchers have known this for decades
Our concept for a support app could help patients with: Learning content on expectation management and relapse Timely reminders to administer and record injections Guidance on injector handling Patient tracking of administration Side-effect tracking, education and mitigation strategies *EMJ European medical journal (2024): High Discontinuation Rates of GLP-1 Agonists in Patients Who Are Obese Motivational holistic weight-loss assistance Integratedmulti-modal support with clear routines could help patients reduce overwhelm, boost motivation and also aid positive habit formation

Phase 2 trial data (NEJM, 2023) showed substantial MRI-PDFF-measured liver fat reductions at 8 mg and 12 mg weekly doses, with some participants falling below the 5% hepatic steatosis threshold

It is also possible that some of the effects of GLP-1 agonists on food intake may be mediated by interaction with sensory afferent neurones of the vagus nerves in the gastrointestinal tract
