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2.4 Assessments Safety assessments included AEs, hypoglycaemic episodes, laboratory safety parameters, physical examination, vital signs and electrocardiogram

Moreover IR in PCOS was shown to destroy the effect of gonadotropins, enhance the sensitivity of follicular membrane cells to the luteinizing hormone, and increase the expression of P450c17 and 3-hydroxysteroid dehydrogenase type 2, leading to increased production of androgen (152)

Both medications are used to promote weight loss, but the way they achieve results can differ slightly

This keeps energy levels stable and reduces overeating caused by sudden hunger

It is not licensed for the treatment of growth hormone deficiency in adults or children in the UK, and its use for weight management, anti-ageing, or performance enhancement is not supported by NICE guidelines

One well-known study found that people on Mounjaro (tirzepatide) often lost more weight than those on semaglutide
