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2.4 Assessments Safety assessments included AEs, hypoglycaemic episodes, laboratory safety parameters, physical examination, vital signs and electrocardiogram

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Moreover IR in PCOS was shown to destroy the effect of gonadotropins, enhance the sensitivity of follicular membrane cells to the luteinizing hormone, and increase the expression of P450c17 and 3-hydroxysteroid dehydrogenase type 2, leading to increased production of androgen (152)

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Both medications are used to promote weight loss, but the way they achieve results can differ slightly

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This keeps energy levels stable and reduces overeating caused by sudden hunger

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It is not licensed for the treatment of growth hormone deficiency in adults or children in the UK, and its use for weight management, anti-ageing, or performance enhancement is not supported by NICE guidelines

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One well-known study found that people on Mounjaro (tirzepatide) often lost more weight than those on semaglutide

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