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Metformin increases plasma ghrelin in Type 2 diabetes

Berberine also modulates gut microbiota composition, increasing populations of bacteria that produce short-chain fatty acids like butyrate, which in turn stimulate GLP-1 release

PLoS One 9:e97554 Lee YS, Jun HS (2016) Anti-inflammatory effects of GLP-1-based therapies beyond glucose control

GLP-1 is a multitasking hormone with wide-ranging physiological effects, particularly in the context of nutrient intake and metabolic control
A large study by Ohno and colleagues, published in Nature in 2020, found that the risk of developing RA rises with every roughly 5 kg of weight gain or every inch added to your waistline

This medication is administered once a week, a schedule designed to maintain steady medication levels in your body, thereby optimizing its effectiveness while minimizing potential side effects
