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Berberine is not recommended during pregnancy or nursing
For weight management, NICE (TA875) recommends semaglutide 2.4 mg (Wegovy) only within specialist weight management services for adults with a BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) and as part of a supervised programme for a maximum of 2 years

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A 15 mg dose becomes exactly 100 units, one full 1 mL syringe
That receptor count helps explain why these medicines are compared, but it should not be used alone to rank them
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