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Description
The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
It works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite
Clinical data suggests patients lose an average of about 2% of body weight per month during the first six months
Clinical testing of these combination therapies will be necessary to determine whether the effects translate to superior weight loss in obese T2DM patients
One in three participants experienced 20% or greater weight loss
Long-term studies indicate that patients can maintain a weight loss of approximately 1015% of their initial body weight after one year of treatment
